Dr.Alslami

ohyeahdevelopmentalbiology:

Some untreatable cancers could soon be held in check by an experimental drug that targets not only the tumour itself, but also how it evolves to spread through the body.

The new drug, Cabozantinib, or cabo for short, simultaneously neutralises two mechanisms cancers need to survive. First, it chokes each tumour’s blood supply by blocking a molecule on the surface of its blood vessels, called vascular endothelial growth factor receptor (VEGFR). There is evidence in animals that cancers can respond to this kind of attack by invading new tissues, where they may be able to generate secondary tumours. Importantly, cabo foils this strategy by blocking a second receptor called c-MET that would otherwise help cancer cells spread to new tissue.

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